Complete Development Of Melanotan 2

Muscle-Building-Human-Growth-Peptide-Hormone-Follistatin-344Melanotan 2 is a synthetic variant of naturally occurring peptide hormone in the body which helps in stimulation of melanogenesis. Melanogenesis is the process by which melanin pigments are produced on the skin. The Alpha Melanocyte stimulating hormone or MSH activates melanocortin receptor. MSH also has influence over appetite, sexual libido, and lipid metabolism through the melanocortin receptors. Hence, Melanotan 2 shows lipolytic, libido enhancing and appetite suppressant properties. It also has the properties of inducing skin tanning, which is said to be useful in protecting skin against ill effects of UVradiations.

Another variant of Melanotan 2, known as PT- 141 is being studied as a remedy for sexual disorders, mainly male erectile dysfunction. Purchasing peptides for research purposes has been made easy with several online sites that sell quality research peptides.

Development of Melanotan 2
The university of Arizona could be credited for the creation of Melanotan 2. Melanotan 2 was primarily synthesized to use as a protection from skin cancer. This works by stimulating melanogenesis, causing the production of the pigment melanin, which protects the skin from direct exposure from UV. Initially, researchers tried to directly harness and administer MSH but it proved very difficult for long-term use, hence a synthetic replacement was made. Melanotan 2 exhibits long half- life, which proves suitable for therapeutic purposes.

Studies on Melanotan 2
Melanotan 2 and Melanotan are analogs of hormone alpha- Melanocyte Stimulating Hormone that induces tanning. Melanotan 2 exhibits aphrodisiac properties, which is not seen in Melanotan 1. This has an additional effect on increasing libido.

Effects of the hormone on mice have been studied in laboratory mice. Central melanocortin was observed to be activated when Melanotan 2 has been fed to the mice. It was also observed that after 6 days of Melanotan treatment there was a loss in adipose tissue and body weight. This has implied that Melanotan may prove useful in the treatment of obesity. Studies have also shown that oxygen consumption has increased in treated mice. Levels of insulin and cholesterol were also seen to be much lower when compared to other treatments.

Alpha-Melanocyte-Stimulating Hormone Analogues
The alpha- melanocyte stimulating hormone is a natural hormone that is important in stimulating melanogenesis, which regulates for skin and hair pigmentation. Alpha-MSH also regulates feeding behavior, sexual activity, and homeostasis. MSH is an agonist of melanocortin receptors MC1, MC3, MC4 and MC 5. Melanotan 1 and 2 stimulate MC1 receptor. This is responsible for skin pigmentation. PT-141 and Melnotan2 stimulate MC3 and MC4 which regulate appetite, sexual behavior, and metabolism. However, MC1 is not stimulated by PT- 141.
Other synthetic analogs of Melanocyte Stimulating Hormone have also been studied for their photoreceptive functions on skin against radiation from sun and UV. These analogs are Melanotan and Melanotan II, which is also known as Melanotan 2. Another analogue of the same hormone, Bremelanotide is under study and development to treat erectile dysfunction.

Only for Research
Even though there is a lot of research on Melanotan 2, the results obtained and the determined effects were only based on animal testing under laboratory condition. It is also important to note that the synthetic peptide is under study and only used for research purposes. All the benefits, functions, and mechanics are based on the results obtained from tests under contained environment.


8 Easy Yet Effective Tips For Beautiful & Healthy Skin

Why-Some-Women-Have-Healthy-Skin-and-Not-You-1024x555-600x300 (1)The time has come when powder advertisements and the annoying fairness creams should be over and folks should be concerned about healthy, beautiful and radiant skin. Thus, rather than jogging behind white skin tone and the paleness, let us learn the best way to get healthy and amazing skin and break the stereotype. A wonderful skin should be fresh, healthy, radiant and even -toned. Here are tricks and some simple methods for amazing skin.

Cosmetics and Bed

The first and the foremost thing you should keep in mind is that never sleep with your makeup on. The skin clogs and makes it unable to respire which results in skin problems like acne, pimples, dark spots, irregular skin tone, etc. So, it is necessary to remove your make-up before getting into bed and try and use oils rather than makeup remover.

0da6c1b266c9c79f4dd79bad3b68bd3cSun Kiss

Sun Kiss seems wonderful, but it’s very dangerous for your skin. Sun can damage your skin and help it become unhealthy. So, it is extremely important if you can not do this constantly wear your sunblock with SPF 30 and to prevent stepping out during peak hours. Wear light clothing which cover maximum parts of your skin if you’ve got to be in the field. Skin exposure leads to age spots, wrinkles, dark patches, tanning and other skin problem.

Eat healthy to not appear ugly

Again among the greatest tricks for amazing skin would be to eat healthy. Based on an old adage, it’s said that you’re what you eat. Eat healthy and avoid junk foods. Food rich in vitamins, mineral and protein is great for skin while hot, fatty, fried, sugary and unhealthy ones lead to pimples, acne, and other skin problem.

Drink Water

The easiest and most straightforward method to get amazing skin would be to drink lots of water. Water makes your skin to appear fresh, radiant and luminous as water flushes away all the toxins out of the body and can help you to be healthy. You should drink at least 8-12 glasses of water daily. Water based veggies and fruits also help you the same manner.


The Four Most Important Benefits of Dark Chocolate

dark-chocolateChocolates are individuals of all ages savories that are relished by individuals of all ages and are something no one would reject. It is added to diverse sweet savories or is eaten as a dessert. It includes cocoa, milk, sugar and other flavors. It should not be consumed if one means to lead a healthy life and is understood to have calories. There’s an option by gorging on dark chocolate to satisfy the sweet tooth. It’s produced using less sugar and therefore does not add on to the calorie content of the pub. After research that was crucial, it is often reasoned that it’s said to have diverse advantages to the body. There are diverse questions that crop up in people’s head when they get to understand about the existence of it alongside the regular bars.

Is it valuable to the health?
It’s understood to have soluble fiber in addition to lots of minerals in it. Minerals like magnesium, copper, iron, phosphorous, zinc, etc. help the body to grow nicely and keep it healthy. The fatty acids found in the cocoa that make up it are saturated and so not difficult to digest making no hints that were dangerous in the body. Additionally it is considered to be rich in antioxidants controlling disorders and that rejuvenate the cells the body.

Dark-Chocolate-Cake_mDoes it change the blood circulation and the heart?
It features flavonols that are known to cause the lining of the arteries in the heart to generate nitric oxide. This gas lets the arteries relax and thereby causing regular blood flow without having low or high blood pressure. The essence in cocoa powder is known to reduce cholesterol levels in men. It thereby shielding the heart and neutralizes the cholesterol levels. The study would have a longer life with a healthy heart and has shown that are likely to face cardiovascular diseases.

• Will the skin have a feel that is better?
Well it’d have a great effect on the skin where the skin is protected by the existence of flavonols from sunlight damage. Skin when exposed to sunlight often has odds of the dangerous UV rays or tanning can cause skin cancer. The contents in the it are understood to hydrate the skin and enhance the blood flow making it seem youthful and thereby making the skin supple.

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